18 November 2008LATEST HIGHLIGHTS
A new cog in a critical signaling machine
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
A previously uncharacterized protein regulates the activity of a receptor in a key molecular mechanism, the Wnt signaling pathway
Deciphering how malaria damages the brain
Walter and Eliza Hall Institute of Medical Research, Australia
Australian researches demonstrate that aggressive T lymphocytes directed against malaria protozoa cause cerebral malaria in mice
Molecules in motion
Institute of Medical Science, University of Tokyo, Japan
A computer simulation has revealed valuable information about the mechanism and regulation of an essential transporter protein
Mediating stress
Institute of Medical Sciences, The University of Tokyo, Japan
A link has been found between the two alternative pathways that are followed by cells subjected to stress
New lead for drugs against HIV
Institute of Medical Science, University of Tokyo, Japan
Derivatives of a common antibiotic can increase resistance to the AIDS-causing virus in white blood cells
Deciphering developmental signaling
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
A genetic screen reveals that in humans and toads a specific phospholipid mediates a signaling pathway with multifarious roles
Prion propagation
Academia Sinica, Taiwan
Mutations in yeast lead to the formation of infectious prions
Base-flipping assists regulation of gene activity
The Institute of Medical Science, The University of Tokyo, Japan
DNA maintains a constant pattern of methylation via a newly identified mechanism
When insulators are not necessarily barriers
National Institute of Immunology, India
The gene locus H19/Igf2 harbors independent transcriptional insulator and chromatin barrier activity
Breast cancer detection gets sweet and sensitive
Academia Sinica, Taiwan
A highly specific, sugar-based assay that detects breast cancer markers could lead to a diagnostic method for use in clinics
Axon amplifiers
Institute for Medical Science, University of Tokyo, Japan
Neuronal activity induces release of calcium from axonal stores, which is required for synaptic plasticity
A need for neurogenesis
Institute for Virus Research, Kyoto University, Japan
Neurogenesis is required for memory formation in the hippocampus, but not in the olfactory bulb, during adulthood.
