Chemistry Articles

Editorial: Data shown

'Data not shown' is an outdated caveat that obscures the transparency of a scientific report and weakens the peer review process.

Nature Chemical Biology, vol. 4 #10, pp575-575

Commentary: Inquiry-based and research-based laboratory pedagogies in undergraduate science

Undergraduate research experiences help retain students in science majors and prepare our workforce for increasingly competitive jobs. Course-based approaches to research and inquiry allow educators to reach larger numbers of students and provide an entry into further research experiences.

Nature Chemical Biology, vol. 4 #10, pp577-580

News and Views: New mechanism for a classic folate inhibitor

Metabolomics reveals new insights into the mechanism of an antimicrobial agent and folate metabolism.

Nature Chemical Biology, vol. 4 #10, pp581-582

News and Views: A bacterial copper metallothionein

Metallothioneins sequester cadmium and surplus atoms of copper and zinc to prevent aberrant metal-catalyzed reactions. The identification of a 'cryptic' copper metallothionein in the bacterium that causes tuberculosis suggests that bacterial metallothioneins may be more widespread than previously suspected.

Nature Chemical Biology, vol. 4 #10, pp582-583

News and Views: Small molecules can have big effects on endurance

Adaptation of muscle to endurance exercise training involves the coordinated expression of genes involved in oxidative metabolism, resulting in increased endurance. A recent study shows that small-molecule activators of two pathways thought to transduce these effects can enhance the effects of training, or even substitute for it.

Nature Chemical Biology, vol. 4 #10, pp583-584

News and Views: Raging hormones in plants

The strigolactones, a known class of plant metabolites, have now been shown to constitute the long-sought hormone that suppresses lateral branch formation. These hormones are synthesized from a carotenoid precursor in the roots and transported to the shoots.

Nature Chemical Biology, vol. 4 #10, pp584-586

News and Views: Sugars stack up

Sugar binding by a variety of biomolecules is generally assumed to rely on hydrogen bonding and ionic interactions. A new study shows that arene-carbohydrate interactions are enthalpically driven through nontraditional C-H···π type hydrogen bonds.

Nature Chemical Biology, vol. 4 #10, pp586-587



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