Immunology : Highlights
: Immunology Articles
Editorial: Celebrating great ideasThis year marks the 100th anniversary of the Nobel Prize in Physiology or Medicine awarded jointly to Paul Ehrlich and Ilya Metchnikov. Nature Immunology, vol. 9 #7, pp693-693 |
Editorial: Science in an open societyA vibrant and eclectic international immunology meeting recently took place in the Arabian Desert of the United Arab Emirates, in the heart of the Islamic world. Nature Immunology, vol. 9 #7, pp693-693 |
News and Views: PTEN gives neutrophils directionNeutrophils can respond to many chemotactic signals, but how these cells 'prioritize' such signals to react to invading pathogens has remained unclear. The phosphatase PTEN seems to be critical in directing the migration of neutrophils toward their end target in a complex milieu of competing signals. Nature Immunology, vol. 9 #7, pp716-718 |
News and Views: Basophils now enhance memoryAdditional immune functions of basophils have been identified in recent years. Mack and colleagues add to this growing list by showing that basophils enhance humoral memory responses by producing interleukins 4 and 6 in response to specific antigen. Nature Immunology, vol. 9 #7, pp720-721 |
News and Views: Nuclear geography and allelic exclusionThe mechanisms responsible for establishing allelic exclusion remain enigmatic. New data indicate that stochastic interactions of antigen-receptor alleles with repressive nuclear compartments may contribute to the mechanisms that support allelic exclusion. Nature Immunology, vol. 9 #7, pp718-720 |
News and Views: New dimensions of CIITACIITA encodes the 'master regulator' of the expression of major histocompatibility complex class II genes. A new layer of complexity has been identified in the control of CIITA expression, which involves the formation of a complex three-dimensional chromatin structure promoted by interactions among many distant regulatory elements. Nature Immunology, vol. 9 #7, pp713-714 |
News and Views: Erg in stem cells: a function emergesTranscription factors of the Ets family are important for mammalian development. A genetic screen now finds that the Ets family member Erg is essential for definitive hematopoiesis and adult hematopoietic stem cell function. Nature Immunology, vol. 9 #7, pp714-716 |