ドイツが優れた科学国家であり続けられるよう、研究者たちはメルケル首相の総選挙勝利を強く望んでいる。
Merkel deserves another term as German chancellor p.5
The former physicist shows a welcome immunity to the mood of anti-science resentment that has infected some democracies.
doi: 10.1038/549005a
The former physicist shows a welcome immunity to the mood of anti-science resentment that has infected some democracies.
doi: 10.1038/549005a
Science must acknowledge mistakes as it marks its past.
doi: 10.1038/549005b
The female bird makes a different and much sneakier sound than the male.
doi: 10.1038/549006a
Advance planning has kept some Texas facilities safe during the unprecedented storm.
doi: 10.1038/nature.2017.22542
Rock-encased bone shard left behind by thieves allowed researchers to determine that the remains are probably more than 13,000 years old.
doi: 10.1038/nature.2017.22521
An international partnership seeks African leadership to organize information about the disease.
doi: 10.1038/nature.2017.22545
Researchers deliberately heated up a slice of the Antarctic sea bed to see how ecosystems responded.
doi: 10.1038/nature.2017.22543
Competing spending priorities in the House of Representative and Senate could push funding negotiations into December.
doi: 10.1038/nature.2017.22548
将来を見通す力とぶれない姿勢が研究の復活の原動力になることを、ドイツは明確に示している。
doi: 10.1038/549018a
固体表面の触媒活性部位の特定と画像化は、大きな科学的課題である。今回、「雑音」を画像化して活性部位をナノメートルスケールの分解能で検出する顕微鏡技術が開発された。
doi: 10.1038/549034a
今回、ヒメツリガネゴケ（Physcomitrella patens）の有性生殖と初期胚発生の両方が、イオンチャネルタンパク質を通した細胞へのカルシウムの流入によって制御されていることが、遺伝子解析から明らかになった。
doi: 10.1038/nature23543
高エネルギー電池の電極は、動作時に壊れることがある。古くからあるロープと滑車の滑車装置から着想を得て、分子スケールで電極をつなぎ留めておけるポリマーが開発され、耐久性のある電池を作製できるようになった。
doi: 10.1038/549037a
ハエは、トランスポゾンから得られたDNA塩基配列のマスターリストを用いて、ウイルスに似た遺伝的寄生体を識別し不活化する。今回、このリスト自体が、トランスポゾンの標的となっている状態を逃れる仕組みが解明された。
doi: 10.1038/549038a
患者の腫瘍細胞をマウスに移植することで、分析と薬物検査用のモデルが得られる。今回、一群の小児固形腫瘍モデルの特徴が広範囲に調べられた。このモデルは自由に無償で利用できるようになっている。
doi: 10.1038/nature23545
量子通信によって、古典的な方法を超える多くの利点が得られるが、これまで信号を送れる距離は数百キロメートルに限定されていた。今回、2つの研究によって、この制限が克服された
doi: 10.1038/549041a
Decoy-state quantum key distribution from a satellite to a ground station is achieved with much greater efficiency than is possible over the same distance using optical fibres.
doi: 10.1038/nature23655
Commensal bacteria have N-acyl amide synthase genes that encode signalling molecules (N-acyl amides) that can interact with G-protein-coupled receptors and elicit host cellular responses similar to eukaryotic N-acyl amides.
doi: 10.1038/nature23874
Transcription of Drosophila PIWI-interacting RNA (piRNA) clusters is enforced through RNA polymerase II pre-initiation complex formation within repressive heterochromatin, accomplished through the transcription factor IIA subunit paralogue Moonshiner.
doi: 10.1038/nature23482
The structures of AMPA receptors in complex with auxiliary proteins are resolved by cryo-electron microscopy, and reveal conformational and permeation pathway changes that are associated with activation and desensitization of ionotropic glutamate receptors.
doi: 10.1038/nature23479
The process that generates Earth’s most intense aurora is found to occur at Jupiter, but is of only secondary importance in generating Jupiter’s much more powerful aurora.
doi: 10.1038/nature23648
Quantum teleportation of single-photon qubits from a ground observatory to a satellite in low-Earth orbit via an uplink channel is achieved with a fidelity that is well above the classical limit.
doi: 10.1038/nature23675
Scanning tunnelling microscopy is used to distinguish between different active sites of a catalyst—such as boundaries between different materials—during a reaction, allowing the contributions of these sites to be evaluated.
doi: 10.1038/nature23661
Metal complexes of the pentazole anion exhibit multiple coordination modes, through ionic, covalent and hydrogen-bonding interactions, and good thermal stability with onset decomposition temperatures greater than 100 °C.
doi: 10.1038/nature23662
On marine islands, most species are good dispersers and most niches are filled by immigration with little adaptive radiation; speciation increases over time, associated with the arrival of weak dispersers that randomly establish isolated populations.
doi: 10.1038/nature23680
Two parallel signalling pathways, driven by Nodal and BMP, respectively integrate left- and right-handed information that drives heart looping and morphogenesis, and are conserved between zebrafish, chicken and mouse.
doi: 10.1038/nature23454
Mutations in genes that encode GLUTAMTATE RECEPTOR-LIKE (GLR) channels in the moss Physcomitrella patens result in failure of motile sperm to target the female reproductive organs and of zygotes to develop properly.
doi: 10.1038/nature23478
A protocol producing orthotopic patient-derived xenografts at diagnosis, recurrence, and autopsy demonstrates proof of principle for using these tumours for basic and translational research on paediatric solid tumours.
doi: 10.1038/nature23647
CMTM6 maintains PD-L1 at the plasma membrane by inhibiting its lysosome-mediated degradation and promoting its recycling.
doi: 10.1038/nature23643
CMTM6 and CMTM4 bind to and stabilize the inhibitory receptor PD-L1 and regulate PD-L1 levels at the surface of human tumour and immune cells.
doi: 10.1038/nature23669
The authors use tiled CRISPR activation for functional enhancer discovery across two autoimmunity risk loci, CD69 and IL2RA, and identify elements with features of stimulus-responsive enhancers, including an IL2RA enhancer that harbours a fine-mapped autoimmunity risk variant.
doi: 10.1038/nature23875
