Volume 22 Number 9

注目のハイライト

その他のハイライト

News

EU to review rare disease drugs market exclusivity

doi: 10.1038/nbt0904-1061

Russia becomes attractive as a source of IP for biotechs

doi: 10.1038/nbt0904-1060

France to focus on a few biotech clusters

doi: 10.1038/nbt0904-1063

As products enter clinic...scientists shown the door.

doi: 10.1038/nbt0904-1059

NAS issues mixed message on unintended effects of GM food

doi: 10.1038/nbt0904-1062

Feature

さようならコロンブス!薬物探索を行わない新たなNRDO企業

Goodbye Columbus! New NRDOs forego discovery

doi: 10.1038/nbt0904-1087

Patents

欧州特許条約が診断法を特許性から除外:見直しの必要

The exclusion of diagnostic methods from patentability by the EPC: a case for review?

doi: 10.1038/nbt0904-1177

News & Views

ホスホプロテオミクスの新次元

Phosphoproteomics finds its timing

doi: 10.1038/nbt0904-1093

腫瘍抗原不要の免疫療法

Immunotherapy dispenses with tumor antigens

doi: 10.1038/nbt0904-1096

銀粒子を用いて酵素特性を明らかにする

Finding enzymatic gold on silver surfaces

doi: 10.1038/nbt0904-1098

期待されるβ細胞前駆体

beta-cell precursors-a work in progress

doi: 10.1038/nbt0904-1095

Letters

リン酸化チロシン依存性シグナル伝達ネットワークの定量的プロテオミクスによる時間的解析

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics p.1139

doi: 10.1038/nbt1005

転写開始部位解析のための5'末端SAGE法

5'-end SAGE for the analysis of transcriptional start sites p.1146

doi: 10.1038/nbt998

キイロショウジョウバエで末端配列削除によって組み込み後安定化したトランスポゾンベクター

Post-integration stabilization of a transposon vector by terminal sequence deletion in Drosophila melanogaster p.1150

doi: 10.1038/nbt1002

2'-O-メチル化RNAを転写する改良型T7 RNAポリメラーゼ変異体

Evolution of a T7 polymerase variant that transcribes 2'-O-methyl RNA p.1155

doi: 10.1038/nbt1001

熱変性を利用してファージ上で選択した凝集しにくいドメインをもつ抗体

Aggregation-resistant domain antibodies selected on phage by heat denaturation p.1161

doi: 10.1038/nbt1000

Computational Biology

Funding high-throughput data sharing

doi: 10.1038/nbt0904-1179

Naturejobs

Strategic HR for today',s biotechnology companies

doi: 10.1038/nbt0904-1189

Opinion and Comment

AIDS, aneuploidy and oncogenes

doi: 10.1038/nbt0904-1077b

Genomic islands in Rhodopseudomonas palustris

doi: 10.1038/nbt0904-1078b

Does biotech M&A benefit investors?

doi: 10.1038/nbt0904-1085

Hydrocarbons and renewable energy

doi: 10.1038/nbt0904-1077a

Reply to ',AIDS, aneuploidy and oncogenes',

doi: 10.1038/nbt0904-1077c

',Informative', horizontal gene transfer

doi: 10.1038/nbt0904-1076b

Reply to ',AIDS, aneuploidy and oncogenes',

doi: 10.1038/nbt0904-1078a

Keeping dry and crossing membranes

doi: 10.1038/nbt0904-1081

Review

遺伝子水平伝播のモニタリングおよびモデリング

Monitoring and modeling horizontal gene transfer p.1110

doi: 10.1038/nbt1006

Review Summary

遺伝子組換え植物の圃場試験での遺伝子水平伝播モニタリングが抱える問題

Problems in monitoring horizontal gene transfer in field trials of transgenic plants

doi: 10.1038/nbt1009

Articles

成体マウス膵臓に由来し神経および膵細胞となる多能性前駆細胞のクローンの同定

Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages p.1115

doi: 10.1038/nbt1004

正常細胞の炎症死を利用した定着腫瘍の簡便な治療法

A simple method to cure established tumors by inflammatory killing of normal cells p.1125

doi: 10.1038/nbt1007

表面増強共鳴ラマン散乱を用いた迅速で超高感度な酵素活性測定法

Rapid and ultra-sensitive determination of enzyme activities using surface-enhanced resonance Raman scattering p.1133

doi: 10.1038/nbt1003

Resources

The exclusion of diagnostic methods from patentability by the EPC: a case for review?

doi: 10.1038/nbt0904-1167

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