The Turkish government must stop university dismissals and commit itself to creating a welcoming research environment if its grand plans for science are to succeed.
doi: 10.1038/542271a
A conservative solution to global warming.
doi: 10.1038/542271b
Psychologists find that Internet trolls seem impervious to any efforts to change their behaviour.
doi: 10.1038/542272a
Agency narrows possible targets for the first-ever sample return from the red planet.
doi: 10.1038/nature.2017.21470
Initiative's first grants will fund a medley of wild ideas from top San Francisco Bay Area biologists, engineers and programmers.
doi: 10.1038/nature.2017.21440
Proposed solution to geometry puzzle allows an object’s structure to be determined from limited information.
doi: 10.1038/nature.2017.21439
International team seeks better picture of wind as it moves over rugged terrain.
doi: 10.1038/542282a
Coalition of scientists and research agencies argue for a one-stop shop server.
doi: 10.1038/nature.2017.21466
Unstable molecule couldn’t be made through conventional synthesis, so IBM researchers carried out molecular surgery using a microscope tip.
doi: 10.1038/nature.2017.21462
トルコは科学基盤を強化して、2023年までに経済大国トップ10入り目指すという野心的な計画を立てているが、これが政治的混乱によって脅かされている。
doi: 10.1038/542286a
最終氷期に、北米を覆っていた氷床から膨大な数の氷山が間欠的に流出した。今回数値モデルから、こうした事象が、概念的に単純なフィードバックサイクルによって生じていたことが示された。
doi: 10.1038/542298a
酵素S6K1がグルタミル-プロリルtRNA合成酵素をリン酸化して代謝活動と寿命を調節することから、重要な代謝シグナル伝達経路の標的としてのこの合成酵素の特殊な役割が明らかになった。
doi: 10.1038/nature21500
技術的な進歩によって、キヌアの複雑なゲノムの塩基配列解読が可能になった。この結果は、ゲノミクスが、主要作物のみならず、世界の食料安全保障に関わる他の植物へとその範囲を大きく拡大していることを浮き彫りにしている。
doi: 10.1038/nature21495
減量手術の影響の1つは、食べ物の好みの変化である。今回、ラットの分析で、腸における栄養シグナルの変化がこの原因であることが示された。迷走神経を活性化して、神経伝達物質ドーパミンによる脳内の信号伝達が増大するのである。
doi: 10.1038/nature21499
酸素は、海洋の生物の大半に不可欠である。今回、過去50年間に全球海洋で酸素濃度が2％低下しており、多くの魚類種や無脊椎動物種の生息地が消失している可能性があることを示す分析結果が報告された。
doi: 10.1038/542303a
2000種を超す鳥類の分析によって、鳥類のくちばしの多様な形状がどのように進化したかについて知見が得られ、鳥類系統の初期の急速な分岐のきっかけが単一のまれな事象であることが示された。
doi: 10.1038/nature21494
Constructing a reference genome for quinoa (Chenopodium quinoa) allows for genetic diversity during the evolution of sub-genomes in quinoa to be characterized and markers that may be used to develop sweet commercial varieties are identified.
doi: 10.1038/nature21370
The formation of the branched epithelial network of the mouse mammary gland during puberty is driven by a heterogeneous population of stem cells at the terminal end buds of the epithelium.
doi: 10.1038/nature21046
The cryo-EM structure of the splicing intermediate known as the C* complex from human.
doi: 10.1038/nature21079
A photovoltage field-effect transistor is demonstrated that is very sensitive to infrared light and has high gain.
doi: 10.1038/nature21050
A class of colloids is reported in which inorganic solute particles—such as metals and semiconductors—are dispersed in molten inorganic salts.
doi: 10.1038/nature21041
Heinrich events — episodes of massive iceberg discharge from the Laurentide Ice Sheet into the North Atlantic Ocean — are triggered by the incursion of warm ocean waters destabilizing the calving front.
doi: 10.1038/nature21069
The oxygen content of the global ocean has decreased by more than two per cent over the past five decades, with large variations found in different ocean basins and at different ocean depths.
doi: 10.1038/nature21399
Analysis of helium isotope ratios in volcanic hotspot lavas suggests that hotter, more buoyant plumes upwelling from the deep mantle entrain high-3He/4He material, unlike cooler, less buoyant plumes, implying the existence of a dense, relatively undisturbed primordial reservoir in the deep mantle.
doi: 10.1038/nature21023
A study of more than 2,000 bird species shows that diversity in bill shape expands towards extreme morphologies early in avian evolution in a series of major jumps, before switching to a second phase in which bills repeatedly evolve similar shapes by subdividing increasingly tight regions of already occupied niche space.
doi: 10.1038/nature21074
Surface area expansion from 6–12 months precedes brain overgrowth in high risk infants diagnosed with autism at 24 months and cortical features in the first year predict individual diagnostic outcomes.
doi: 10.1038/nature21369
Single-molecule fluorescence in situ hybridization is performed to identify several landmark genes in the liver and their level of expression in single-cell RNA sequencing is used to spatially reconstruct the zonation of all liver genes.
doi: 10.1038/nature21065
Glutamyl-prolyl tRNA synthetase (EPRS) is a downstream effector of the mTORC1–S6K1 signalling axis and contributes to adiposity and ageing in mice.
doi: 10.1038/nature21380
Depletion of Smarcb1 activates the Myc network of signalling cascades, increasing protein metabolism and activation of survival pathways allowing highly aggressive Kras-independent pancreatic cancer cells to develop.
doi: 10.1038/nature21064
Adult neurons from Caenorhabditis elegans can extrude large membrane-surrounded vesicles, known as exophers, containing protein aggregates and dysfunctional organelles that threaten neuronal homeostasis.
doi: 10.1038/nature21362
Crystal structures of engineered human MFN1 in different stages of GTP hydrolysis provide insights into the GTP-induced conformational changes that promote MFN1 dimerization to bring about mitochondrial fusion.
doi: 10.1038/nature21077
The cryo-electron microscopy structure of a yeast spliceosome stalled before mature RNA formation provides insight into the mechanism of exon ligation.
doi: 10.1038/nature21078
