Psychology can moderate our response to unsavoury actions such as the US ban on immigrants, but we should not let our appetite for dissent diminish.
doi: 10.1038/542005a
Earth-monitoring research missions should go on, despite commercial ventures
doi: 10.1038/542005b
As the public-health agency chooses a new leader, the media and politicians must be more realistic about what it can do.
doi: 10.1038/542006a
Order barring citizens of seven countries from entering the United States has left many confused and afraid.
doi: 10.1038/nature.2017.21389
Until this obstacle is overcome, the technology is unlikely to succeed in the wild.
doi: 10.1038/542015a
Neural networks produce pictures to train image-recognition programs and scientific software.
doi: 10.1038/542016a
Many researchers are sceptical of a paper claiming to have compressed hydrogen to a metallic state.
doi: 10.1038/nature.2017.21379
A movement to privatize Earth-observing satellites is gaining ground.
doi: 10.1038/542018a
Centre evaluates how public-health spending can improve mortality rates and disease burden, but many countries still do not record how people die.
doi: 10.1038/nature.2017.21373
地球から最も近い太陽系外惑星プロキシマ・ケンタウリbを探査するという大胆な計画が形になりつつある。
doi: 10.1038/542020a
エアコンの需要が高まる中で、暑さの元凶である「太陽光」を使った冷却法の研究が行われている。
doi: 10.1038/542023a
がん細胞が腫瘍抑制遺伝子を欠失している場合、近傍の遺伝子も欠失している。こうした近傍の遺伝子の1つに重要な代謝的役割があることが分かり、多くの腫瘍に適している可能性がある治療機会が明らかになった。
doi: 10.1038/nature21117
電子顕微鏡法と画像シミュレーションを組み合わせて、金属合金ナノ粒子内の原子の位置が決定され、粒子の構造と磁気特性の関連が明らかになった。
doi: 10.1038/542035a
今回、画像解析のみを用いて皮膚がんを分類するよう学習させたコンピューターが、皮膚がん専門医と同程度の正確さでがんを識別できた。これは、医療診断の未来にどれほどの影響をもたらすのだろうか。
doi: 10.1038/nature21492
世界最大の可能性がある連続的な熱帯泥炭複合体が見つかった。これは、全球の炭素貯蔵や、アフリカ中部における土地管理と科学的投資に大きな影響を与える。
doi: 10.1038/542038b
増殖因子のTGF-β1はかご状タンパク質の中にあり、インテグリンタンパク質と結合することで力が加わり放出されると考えられている。今回、インテグリンのαVβ6と複合体を形成したTGF-β1の構造から、こうした放出過程が明らかになった。
doi: 10.1038/nature21119
2015年に提案された仮説では、河川網の再編成によって山岳地帯の比較的平坦な地表が形成されたことが示唆された。今回新たな解析によってこの考えが反証され、地球科学における長年の課題に関する議論に再び火がついた。
doi: 10.1038/542041a
Interleukin-17 functions as a neuromodulator in the roundworm Caenorhabditis elegans, acting directly on RMG hub interneurons to alter their response properties and contribution to behaviour.
doi: 10.1038/nature20818
The lymphangiogenic factor PROX1 transcriptionally upregulates CPT1A, a rate-controlling enzyme in fatty acid β-oxidation, and this co-regulates lymphatic endothelial cell differentiation by epigenetic control of lymphatic gene expression, demonstrating a role for metabolism in developmental biology.
doi: 10.1038/nature21028
Integrin αVβ6 binds the transforming growth factor-β1 precursor (pro-TGF-β1) in an orientation that is biologically relevant for force-dependent release of TGF-β from its latent form.
doi: 10.1038/nature21035
The first high-resolution (3.5 Å) structure of a full-length cyclic-nucleotide-gated channel, revealing an unconventional, voltage-insensitive voltage-sensor domain and a unique coupling mechanism between cyclic-nucleotide-binding and pore-opening.
doi: 10.1038/nature20819
Spin–orbit coupling is implemented in an optical lattice clock using a narrow optical transition in fermionic 87Sr atoms, thus mitigating the heating problems of previous experiments with alkali atoms and offering new prospects for future investigations.
doi: 10.1038/nature20811
Ultrafast photo-magnetic recording in transparent films of the dielectric cobalt-substituted garnet has very low heat load and is much faster than existing alternatives.
doi: 10.1038/nature20807
The three-dimensional coordinates of more than 23,000 atoms in an iron-platinum nanoparticle are determined with 22 picometre precision to correlate chemical order/disorder and crystal defects with magnetic properties.
doi: 10.1038/nature21042
Substitution of a ligand in molybdenum-based complexes enables typically inert hexafluorobutene to participate in Z-selective olefin cross-metathesis reactions.
doi: 10.1038/nature21043
Field measurements combined with remotely sensed data reveal the Cuvette Centrale in the central Congo Basin to contain the most extensive peatland complex in the tropics, increasing the best estimate of global tropical peatland carbon stocks by approximately one-third.
doi: 10.1038/nature21048
Examination of the ecosystem properties of treeline ecotones in seven temperate regions of the world shows that the reduction in temperature with increasing elevation does not affect tree leaf nutrient concentrations, but does reduce ground-layer community-weighted plant nitrogen levels, leading to a strong stoichiometric convergence of ground-layer plant community nitrogen to phosphorus ratios across all regions.
doi: 10.1038/nature21027
Competitive circuits in the amygdala of mice drive either freezing or flight behaviour in response to threat, and involve distinct neuronal subtypes.
doi: 10.1038/nature21047
The genome sequences of the neglected human-infective malaria species Plasmodium malariae and P. ovale provide new insights into their biology that are pertinent to understanding their epidemiology and to the broader agenda of malaria elimination.
doi: 10.1038/nature21038
A frame-shift mutation in MATRILINEAL, a pollen-specific phospholipase, triggers haploid induction in maize, which may be useful in developing improved haploid induction systems for crop breeding.
doi: 10.1038/nature20827
The authors identify in patients with rheumatoid arthritis a pathogenic subset of CD4+ T cells that augments B cell responses within inflamed tissues.
doi: 10.1038/nature20810
An artificial intelligence trained to classify images of skin lesions as benign lesions or malignant skin cancers achieves the accuracy of board-certified dermatologists.
doi: 10.1038/nature21056
Depletion of malic enzyme 3 in pancreatic cancer cells that have a deletion of the gene for malic enzyme 2 selectively kills the cells, suggesting that the enzyme might represent a therapeutic target for this subset of cancers.
doi: 10.1038/nature21052
