Funding trouble at flagship research centre reflects a broader malaise in the country’s scientific priorities that must be addressed.
doi: 10.1038/nature.2017.22444
Science cannot and should not be used to justify prejudice.
doi: 10.1038/548259b
Effort backed by the state’s flagship universities comes as US President Donald Trump shrugs off global warming.
doi: 10.1038/548267a
Hub aims to make industrial-scale high-resolution brain mapping a standard tool for neuroscience
doi: 10.1038/548268a
Disruptive weather pattern in 2014–2016 spurred tropical forests to pump out 3 billion tonnes of carbon.
doi: 10.1038/nature.2017.22440
Science panel says institutions need to do more to prevent and mitigate damage to research equipment and animals.
doi: 10.1038/nature.2017.22446
Protesters demand respect for research — but some scientists were told to stay away.
doi: 10.1038/nature.2017.22439
Multi-lab efforts point the way to shoring up the reliability of field studies.
doi: 10.1038/548271a
倫理面などで懸念はあるが、中国では着床前遺伝子診断が急激に増えている。
doi: 10.1038/548272a
北大西洋の水温変動は、競合する多数の物理過程の結果であるが、こうした過程の相対的な役割は論争の源である。今回、こうした論争について、展望が2つ示された。
doi: 10.1038/nature23538
苦みや甘みなどの味覚に関する情報は、それぞれの味覚に固有の経路を通してマウスの舌から脳へ伝えられる。今回、セマフォリンタンパク質が、こうした経路の配線を誘導していることが分かった。
doi: 10.1038/nature23537
原発部位から体の別の部位に広がった500例のヒトがんのDNAとRNAの塩基配列によって、基礎科学と患者の利益の一致に一歩近づいた。
doi: 10.1038/nature23535
赤色超巨星の外層大気におけるガスの動的運動がマッピングされ、恒星風を通して大質量星が質量を失う原因となる未知の機構の手掛かりが得られた。
doi: 10.1038/548288a
ライブ画像化法によって、健康な皮膚細胞が、がんを促進する変異を持つ隣接細胞を取り囲んで排除することが示され、組織が変異細胞を認識し除去して腫瘍のイニシエーションを妨げ得ることが明らかになった。
doi: 10.1038/nature23534
Maiopatagium, a haramiyid from the Jurassic Tiaojishan Formation (around 160 million years ago) of China was specialised for gliding with a patagium (wing membrane) and a fused wishbone, reminiscent of that of birds.
doi: 10.1038/nature23476
Clinical exome and transcriptome sequencing of 500 adult patients with metastatic solid tumours of diverse lineage and biopsy site, as part of the Michigan Oncology Sequencing (MI-ONCOSEQ) Program.
doi: 10.1038/nature23306
The majority of ‘jellyfish’ galaxies, characterized by long ‘tentacles’ of gas, also have active nuclei, indicating that gas is being fed to the central supermassive black hole by ram pressure.
doi: 10.1038/nature23462
Mapping the velocity of the gas at the surface and in the atmosphere of the nearby red supergiant star Antares reveals vigorous motion of several huge gas clumps in an extended atmosphere, which cannot be fully explained by convection.
doi: 10.1038/nature23445
Electronic nematicity is observed in a heavy-fermion superconductor, CeRhIn5, suggesting a close link between unconventional superconductivity and the appearance of nematicity.
doi: 10.1038/nature23315
A relaxation oscillator incorporating nanoscale niobium dioxide memristors that exhibit both a current- and a temperature-controlled negative differential resistance produces chaotic dynamics that aid biomimetic computing.
doi: 10.1038/nature23307
Morphological analysis of teeth found at Lida Ajer shows that these belong to Homo sapiens, indicating that modern humans were in Sumatra between 73,000 and 63,000 years ago.
doi: 10.1038/nature23452
The fossil of a gliding mammal from the Tiaojishan Formation of China displays many unique features of its ears, teeth and tooth-replacement pattern, illustrating the great diversity of stem mammals living in the Jurassic period.
doi: 10.1038/nature23483
Taste-receptor cells use distinct semaphorins to guide wiring of the peripheral taste system; targeted ectopic expression of SEMA3A or SEMA7A leads to bitter neurons responding to sweet tastes or sweet neurons responding to bitter tastes.
doi: 10.1038/nature23299
Intravital imaging reveals unanticipated plasticity of adult skin epithelium in mice when faced with mutational or non-mutational insults, and elucidates the dynamic cellular behaviours used for its return to a homeostatic state.
doi: 10.1038/nature23304
The authors assess the role of N 6-methyladenosine in T cell development and function, and show that RNA methylation controls T cell homeostasis by regulating IL-7-mediated STAT5 activation.
doi: 10.1038/nature23450
Long noncoding RNAs are investigated using a CRISPR–Cas9 activation screen and shown to confer BRAF inhibitor resistance on melanoma cells through various local mechanisms.
doi: 10.1038/nature23451
TUT4 and TUT7 mediate 3′ uridylation of mRNA transcripts, preferentially those with short poly(A) tails; in the absence of TUT4 and TUT7, oocytes cannot mature and female mice are infertile.
doi: 10.1038/nature23318
The structure of yeast Hrd1 in complex with Hrd3 shows that Hrd1 forms an aqueous cavity with a lateral seal within the endoplasmic reticulum membrane, shedding light on how misfolded proteins are transported out of the endoplasmic reticulum.
doi: 10.1038/nature23314
Determination of the crystal structure of the zebrafish LPA6 receptor shows that the lipid ligand binds to an unusual ligand-binding pocket in the receptor that is laterally accessible through the membrane.
doi: 10.1038/nature23448
