国際単位系(SI)には問題点もあり、見直しが必要だ。
SI units need reform to avoid confusion p.135
A flaw in the system leaves physicists grappling with dimensionless units.
doi: 10.1038/548135b
A flaw in the system leaves physicists grappling with dimensionless units.
doi: 10.1038/548135b
It’s time for researchers to lend their expertise to expediting the arrival of cutting-edge therapies that are waiting in the wings.
doi: 10.1038/548135a
Odd results could still be consistent with the ‘standard model’ of cosmology.
doi: 10.1038/nature.2017.22413
Scientific network aims to train a generation of African leaders in primate research.
doi: 10.1038/548144a
Women with sleep disorders were about twice as likely to deliver babies more than six weeks early.
doi: 10.1038/nature.2017.22419
From ground, sky and space, researchers are ready to test latest technologies on the Great American Eclipse.
doi: 10.1038/548146a
Non-scientists are being recruited to collect data on everything from the Sun’s outer atmosphere to animal behaviour.
doi: 10.1038/nature.2017.22415
US firm AquaBounty Technologies says that its transgenic fish has hit the market after a 25-year wait.
doi: 10.1038/nature.2017.22116
ニューロンについては単純な回路ですら解明は困難であり、何十億個もの細胞を持つ脳の複雑なネットワークを理解するには、新しい脳マッピング技術が必要となる。
doi: 10.1038/548150a
類人猿の進化系統樹については、類人猿とヒトの祖先が分岐する以前の初期進化の化石証拠が不足している。今回、1300万年前の頭蓋骨から、当時の類人猿の発生に関する知見が得られた。
doi: 10.1038/548160a
光共振器と呼ばれるデバイスを用いた従来型のセンサーには、感度に基本的な限界がある。今回、精密に調節することによってこの制約が克服され、超精密センシングへの扉が開かれた。
doi: 10.1038/548161a
BET阻害剤と呼ばれる有望な抗がん剤の活性の詳細は、まだよく分かっていない。今回、クリック化学という方法によって、こうした薬剤が重要な標的タンパク質であるBRD4の機能を調節する仕組みを綿密に調べることができるようになった。
doi: 10.1038/548162a
20世紀において、生態系が干ばつから回復するのにかかる時間が長くなっていることが、解析によって示された。干ばつ事象の頻度が今後増えれば、一部の生態系が完全に回復する機会を失う可能性がある。
doi: 10.1038/548164a
ほぼ全ての細胞タイプになる能力は、卵子、精子、最初期胚の始原幹細胞に限定されている。今回、2報の論文によって、この多能性状態をin vitroで維持するためには代償を伴うことが明らかになった。
doi: 10.1038/nature23102
モデル化法を用いて、さまざまな種の間の競争が調べられ、複数の競争者間の相互作用が生物多様性の維持に役立つ仕組みに関する知見が得られた。
doi: 10.1038/nature23103
Description of the most complete fossil skull of an infant ape recovered from the Miocene epoch of Kenya, assigned to a new species in the genus Nyanzapithecus.
doi: 10.1038/nature23456
The complete, synapse-resolution connectome of the Drosophila larval mushroom body.
doi: 10.1038/nature23455
In an analysis of a large sample of microlensing events, a few suggest the existence of Earth-mass free-floating planets, but only the expected number of Jupiter-mass free-floating objects were detected.
doi: 10.1038/nature23276
The response of a ternary, parity–time-symmetric system that exhibits a third-order exceptional point increases as a function of the cube-root of induced perturbations.
doi: 10.1038/nature23280
Tuning optical microcavities to exceptional points enhances their ability to sense nanoscale objects, owing to the topological features of exceptional points.
doi: 10.1038/nature23281
A bottom-up process to achieve rapid growth of micrometre-sized three-dimensional nanocrystal superlattices during colloidal synthesis at high temperatures is revealed by in situ small-angle X-ray scattering; the process is applicable to several colloidal materials.
doi: 10.1038/nature23308
A global analysis of gross primary productivity reveals that drought recovery is driven by climate and carbon cycling, with recovery longest in the tropics and high northern latitudes, and with impacts increasing over the twentieth century.
doi: 10.1038/nature23021
The pollination service provided by nocturnal flower visitors is disrupted near street lamps, which leads to a reduced reproductive output of the plant that cannot be compensated for by daytime pollinators; in addition, the structure of combined nocturnal and diurnal pollination networks facilitates the spread of the consequences of disrupted night-time pollination to daytime pollinators.
doi: 10.1038/nature23288
Communities that are very rich in species could persist thanks to the stabilizing role of higher-order interactions, in which the presence of a species influences the interaction between other species.
doi: 10.1038/nature23273
New genome-wide data for ancient, Bronze Age individuals, including Minoans, Mycenaeans, and southwestern Anatolians, show that Minoans and Mycenaeans were genetically very similar yet distinct, supporting the idea of continuity but not isolation in the history of populations of the Aegean.
doi: 10.1038/nature23310
Long-term culture of male embryonic stem cells in naive conditions containing Mek1/2 and Gsk3a/b inhibitors leads to irreversible changes in epigenetic and genomic stability that compromise their in vivo developmental potential.
doi: 10.1038/nature23274
Derivation of female mouse embryonic stem cells under certain conditions induces a loss of DNA methylation and erasure of genomic imprints, which are not recovered and that may contribute to observed impaired development.
doi: 10.1038/nature23286
Metabolic changes in T cells can affect the genomic methylation status of key transcription factors and regulate the fate decision between induced regulatory T cells and T helper 17 cells.
doi: 10.1038/nature23475
Hypoactive BRAF mutants bind more tightly than wild type to the upstream regulator RAS, thus amplifying ERK signalling; tumours expressing these mutants require coexistent mechanisms for RAS activation to grow and are sensitive to their inhibition.
doi: 10.1038/nature23291
Kinase-inactive Braf mutants can initiate the development of lung adenocarcinoma in mice; co-expression of activated Kras enhances tumour initiation and progression, and wild-type Braf is required to sustain tumorigenesis.
doi: 10.1038/nature23297
Introducing a single ‘sticky’ (hydrophobic) amino acid by point mutation into symmetric protein complexes frequently triggers their association into higher-order assemblies, without affecting their native fold and structure.
doi: 10.1038/nature23320