博士過程の学生がその後の進路を適切に選べるよう、支援が必要だ。
Many junior scientists need to take a hard look at their job prospects p.429
Permanent jobs in academia are scarce, and someone needs to let PhD students know.
doi: 10.1038/550429a
Permanent jobs in academia are scarce, and someone needs to let PhD students know.
doi: 10.1038/550429a
The US Department of Energy should classify and dispose of nuclear rubbish according to risk.
doi: 10.1038/550429b
Online platforms can help to steer emergency response and ensure money is well spent.
doi: 10.1038/550430a
Juno probe discovers surprising activity in the giant planet’s interior.
doi: 10.1038/nature.2017.22866
Discovery raises questions about how a light 'supercurrent' might behave.
doi: 10.1038/nature.2017.22868
Precision tools expand the number of ‘base editors’ available for manipulating DNA and RNA.
doi: 10.1038/550439a
The Chandrayaan-2 orbiter, lander and rover will track how lunar dust might scupper settlement.
doi: 10.1038/nature.2017.22870
Researchers seek approval from regulators for this quicker, easier treatment.
doi: 10.1038/nature.2017.22856
US-registered Central European University faces another year of uncertainty over whether it can continue to operate in Hungary.
doi: 10.1038/nature.2017.22855
シリア内戦は、危機的状況下でのデータ収集・活用・管理の方法を模索する場となっている。
doi: 10.1038/550444a
マウスにおいて、自分では死なない細胞を殺すことが強力な抗加齢戦略だと分かり、この戦略のヒトでの研究が進められている。
doi: 10.1038/550448a
上皮幹細胞は、皮膚の表皮を維持し、損傷に応答して創傷治癒を促進する。今回、こうした幹細胞が過去の損傷の記憶を持っていて、この記憶によって皮膚がその後の脅威に対して速やかに応答できるという知見が得られた。2つの分野の科学者がこの知見の意味合いについて検討している。
doi: 10.1038/nature24154
レーザー実験とコンピューターシミュレーションを用いて、圧縮された固体中の原子の小刻みな揺れが分析された。この結果によって、極端な条件に耐えられる材料の設計にさらに一歩近づいた。
doi: 10.1038/550461a
バレット食道と呼ばれる前がん状態の細胞起源は分かっていない。今回行われた患部の上皮細胞の追跡と分析は、この問題の解明に役立つ可能性がある。
doi: 10.1038/nature24150
カタビロアメンボ科Rhagovelia属のアメンボは、足に推進用の扇があるおかげで、急流を容易に移動できる唯一の昆虫分類群である。今回、こうした扇の発生を制御する遺伝子が特定され、この昆虫が環境にどのように適応してきたかについての手掛かりが得られた。
doi: 10.1038/550464a
今回、超高感度天秤が開発され、高い時間分解能と質量分解能で単一細胞と複数の細胞の重さが測定された。この結果から、細胞周期とウイルス感染時における急速で微小な質量の変動が明らかになった。
doi: 10.1038/550465a
粒子を多く含む液滴が固体表面で蒸発すると、粒子によって環状の堆積物が形成される。この現象の説明は、1997年に示され、理工学の多くの分野を進展させた。
doi: 10.1038/550466a
さまざまな花の花弁には、種を超えて同程度の不規則性を示す繰り返しパターンのナノ構造がある。この不規則性の程度から、青色の散乱光の輪が生じ、ハナバチが花を見つけるのに役立つ。
doi: 10.1038/nature24155
Disordered nanoscale striations on petals, tepals and bracts have evolved multiple times among flowering plants and provide a salient visual signal to foraging bumblebees (Bombus terrestris).
doi: 10.1038/nature24285
After acute inflammation, epithelial stem cells retain a memory that accelerates restoration of the skin barrier during subsequent tissue damage, and this enhancement is dependent on the AIM2 inflammasome and its downstream effectors.
doi: 10.1038/nature24271
Small molecules are identified that inhibit the ubiquitin-specific protease USP7 with high affinity and specificity as explained by co-crystal structures, and are shown to reduce tumour growth in mice.
doi: 10.1038/nature24451
A structural phase transition in a monolayer of molybdenum ditelluride has been shown experimentally to be driven forwards and backwards by electrostatic doping.
doi: 10.1038/nature24043
The limits of dislocation-mediated metal plasticity are studied by using in situ computational microscopy to reduce the enormous amount of data from fully dynamic atomistic simulations into a manageable form.
doi: 10.1038/nature23472
In situ femtosecond X-ray diffraction measurements reveal that the dominant mechanism of shock-wave-driven deformation in tantalum changes from twinning to dislocation slip as pressure increases.
doi: 10.1038/nature24061
A picobalance consisting of an optically excited microcantilever has been developed and used to measure the masses of individual healthy and virus-infected cells at high temporal and mass resolutions in culture conditions.
doi: 10.1038/nature24288
Plough marks in Pine Island Bay, West Antarctica, left by the keels of drifting icebergs 12,000 years ago provide evidence that marine ice-cliff instability can drive rapid ice-sheet retreat.
doi: 10.1038/nature24458
An approach to ecological interactions that integrates coevolutionary dynamics and network structure, showing that selection in mutualisms is shaped not only by the mutualistic partners but also by all sorts of indirect effects from other species in the network.
doi: 10.1038/nature24273
Spatial and temporal modelling of a large dataset of Plasmodium falciparum prevalence rates reveals cycles and trends of malaria transmission in sub-Saharan Africa over a 115 year period.
doi: 10.1038/nature24059
Application of network control theory to the neuronal connectome of Caenorhabditis elegans, allowing prediction of the involvement of individual neurons in locomotion.
doi: 10.1038/nature24056
Identification of a transmembrane protein, Mfsd2b, that is essential for the export of the signalling molecule sphingosine-1-phosphate (S1P) from red blood cells and platelets.
doi: 10.1038/nature24053
Barrett’s oesophagus—a metaplasia that can be induced by persistent acid reflux, and predisposes patients to oesophageal cancer—arises from a population of basal cells at the gastro-oesophageal junction.
doi: 10.1038/nature24269
The development of selective ubiquitin-specific protease-7 (USP7) inhibitors GNE-6640 and GNE-6776, which induce tumour cell death and reveal differential kinetics of Lys-48 and Lys-63-linked ubiquitin chain depolymerization by USP7.
doi: 10.1038/nature24006
A cryo-electron microscopy structure of the chromatin remodelling factor Chd1 bound to a nucleosome leads to a model for DNA translocation by its ATPase motor.
doi: 10.1038/nature24046
G-protein-coupled receptors and their G protein partners are studied by single-molecule imaging in living cells, which reveals hot spots on the cell membrane where receptors and G proteins interact and signal.
doi: 10.1038/nature24264
