仕事の自動化が雇用に及ぼす影響について、考えるべき時だ。
Science must examine the future of work p.301
As automation changes employment, researchers should gather the evidence to help map the implications.
doi: 10.1038/550301b
As automation changes employment, researchers should gather the evidence to help map the implications.
doi: 10.1038/550301b
Time to think about how automation will affect employement.
doi: 10.1038/550301a
Flowers have evolved an ingenious way to attract pollinators.
doi: 10.1038/550302a
Stellar collision confirms theoretical predictions about the periodic table.
doi: 10.1038/550309a
Concern mounts over budget cuts and other changes that undermine basic science.
doi: 10.1038/550310a
The agency's plan to reverse limits on greenhouse-gas emissions is likely to draw legal challenges.
doi: 10.1038/nature.2017.22813
Metrologists are poised to change how scientists measure the Universe.
doi: 10.1038/550312a
Therapy that targets disease-causing mutations could become the first of its kind approved for use in the United States.
doi: 10.1038/nature.2017.22819
デジタル技術が仕事をどのように変貌させるかは、しっかりと調べることで見えてくる。
doi: 10.1038/550315a
デジタル革命が世界の労働力をどのように変えていくのか、3つの疑問から考える。
doi: 10.1038/550316a
「アルファ碁ゼロ」と呼ばれる人工知能プログラムは、人間の対局データや定石なしに碁を習得した。この成果の意味合いについて、1人のコンピューター科学者と2人の米国囲碁協会会員が検討している。
doi: 10.1038/550336a
腫瘍細胞は、化学療法への感受性を弱めるような内因性の適応を発達させることがある。今回、腫瘍細胞が、外因性の細菌の活性によっても薬物療法の影響から逃れられるようになることが分かった。
doi: 10.1038/550337a
機械学習と量子計算を組み合わせた手法を用いて、「ヒッグス粒子」と呼ばれる粒子が同定された。この方法は、科学の多くの分野で応用できる可能性がある。
doi: 10.1038/550339a
炎症性の応答は、老化に伴う分泌の表現型であり、成長、加齢、がんに影響を及ぼすことがある。今回、こうした応答のきっかけの1つが、細胞質内のDNAの存在であることが明らかになった。
doi: 10.1038/nature24146
壊れたDNAの修復は、ゲノム安定性や、がんの進行を妨げるのに極めて重要である。今回、腫瘍抑制タンパク質BRCA1が、相同組換えと呼ばれるDNA修復経路をどのようにして活性化するかが示された。
doi: 10.1038/nature24149
レット症候群は、破壊された形態のMECP2タンパク質に起因する脳疾患であるが、MECP2の喪失が脳にどのように影響を及ぶすかは分かっていない。今回、マウスの研究で、このタンパク質の重要な領域が明らかになり、治療に関わる知見が得られた。
doi: 10.1038/nature24151
The history and future potential of DNA sequencing, including the development of the underlying technologies and the expansion of its areas of application, are reviewed.
doi: 10.1038/nature24286
Starting from zero knowledge and without human data, AlphaGo Zero was able to teach itself to play Go and to develop novel strategies that provide new insights into the oldest of games.
doi: 10.1038/nature24270
The tumour suppressor complex BRCA1–BARD1, which facilitates the generation of a single-stranded DNA template during homologous recombination, also binds to the recombinase RAD51 and enhances its function.
doi: 10.1038/nature24060
Two structures of human transient receptor potential mucolipin 1 (TRPML1), in the closed and agonist-bound open states, have been resolved by electron cryo-microscopy.
doi: 10.1038/nature24036
The magnetic moment of the antiproton is measured at the parts-per-billion level, improving on previous measurements by a factor of about 350.
doi: 10.1038/nature24048
A machine learning algorithm implemented on a quantum annealer—a D-Wave machine with 1,098 superconducting qubits—is used to identify Higgs-boson decays from background standard-model processes.
doi: 10.1038/nature24047
Cations are used to control the interlayer spacing of graphene oxide membranes, enabling efficient and selective sieving of hydrated cations.
doi: 10.1038/nature24044
A blend of two organic molecules excited by a simple LED light source can release the stored excitation energy slowly as ‘long persistent luminescence’ over periods of up to an hour.
doi: 10.1038/nature24010
Interactions with male and female intruders activated overlapping neuronal populations in the ventromedial hypothalamus of inexperienced adult male mice, and these ensembles gradually separated as the mice acquired social and sexual experience with conspecifics.
doi: 10.1038/nature23885
Cultures of expanded potential stem cells can be established from individual eight-cell blastomeres, and by direct conversion of mouse embryonic stem cells and induced pluripotent stem cells, highlighting the feasibility of establishing expanded potential stem cells for other mammalian species.
doi: 10.1038/nature24052
Analysis of the minimal functional unit for MeCP2 protein shows that its function is to recruit the NCoR/SMRT co-repressor complex to methylated sites on chromatin, which may have use in designing strategies for gene therapy of Rett syndrome.
doi: 10.1038/nature24058
Cytoplasmic chromatin activates the innate immunity cytosolic DNA-sensing cGAS–STING pathway, leading both to short-term inflammation to restrain activated oncogenes and to chronic inflammation that associates with tissue destruction and cancer.
doi: 10.1038/nature24050
A new engineered version of SpCas9, called HypaCas9, displays enhanced accuracy of editing without significant loss of efficiency at the desired target.
doi: 10.1038/nature24268
A cryo-electron microscopy structure shows that the mucolipin domain of the lysosomal calcium channel TRPML3 binds phosphatidylinositol-3,5-bisphosphate and gates the channel.
doi: 10.1038/nature24055
The structure of mouse transient receptor potential mucolipin 1 (TRPML1), a cation channel located within endosomal and lysosomal membranes, is resolved using single-particle electron cryo-microscopy.
doi: 10.1038/nature24035
