A feat in stem-cell therapy highlights what can be achieved when basic and clinical research combine to advance biological understanding and treatment.
doi: 10.1038/551141a
Researchers should recognize communities that feel over-researched and under-rewarded.
doi: 10.1038/551141b
The US environment agency should not ban researchers it funds from its advisory boards.
doi: 10.1038/551142a
Success for the ‘Arctic apple’ could herald a new wave of lab-grown foods.
doi: 10.1038/551149a
Analysis of universities' salary data suggests major disparities in pay for early-career researchers.
doi: 10.1038/nature.2017.22932
The first new species of great ape described in more than eight decades faces threats to its habitat.
doi: 10.1038/nature.2017.22934
Rare move stems from a conflict over two journal articles about renewable energy.
doi: 10.1038/nature.2017.22944
Conclusions of climate-change science analysis are at odds with US President Donald Trump’s policies.
doi: 10.1038/nature.2017.22958
Physicists begin to embrace alternative explanations for the missing material.
doi: 10.1038/551153a
広く使われているネオニコチノイド系農薬を禁止しようという動きが、激しい論争を引き起こしている。
doi: 10.1038/551156a
今回、シリコンプローブをマウスの脳に挿入して、約200個のニューロンの活動を同時に精密記録することができた。このツールによって、機能的な神経回路を調べる能力が改善されるはずである。
doi: 10.1038/551172a
初期には通常の超新星爆発に似ていたイベントが、600日以上にわたって輝き続けた。標準的な理論モデルでは、このイベントの特性を説明できない。
doi: 10.1038/551173a
メッセンジャーRNA（mRNA）のアデニン塩基には、N1メチル基が広く存在すると考えられていた。今回、こうした修飾はそれほど一般的でなく、トランスファーRNAを構造的に模倣したmRNA上で生じているらしいことが分かった。
doi: 10.1038/nature24156
スペクトルの短波長赤外域で蛍光を発する小分子有機色素によって、in vivo生体画像化法の分解能が改善される可能性がある。今回、可視光の蛍光を発する色素を改造して、そうした色素が作られた。
doi: 10.1038/nature24755
コンピューターシミュレーションによって、極めて小さい氷の結晶内部の水分子は、バルク氷に見られるような配置をとる傾向がないことが示された。この知見は、気象予報に影響を及ぼす。
doi: 10.1038/551178a
海洋の最も密度の高い水の循環は、気候の千年スケールの変化を調節している。従来の知識に反して、こうした海水が海面へ上昇する位置を海底の形が制約していることが、今回分かった。
doi: 10.1038/551178b
今回、神経ペプチドのシグナル伝達経路の遺伝的多様性が、加齢に伴う線虫の健康の衰えを調節していることが分かった。この発見は、老化の個体差に影響を及ぼす機構を示している。
doi: 10.1038/551179a
The geometry of the ocean floor sets key regime transitions in the circulation of deep ocean waters.
doi: 10.1038/nature24472
Fragmentation of forest ecosystems produces forest edges, which affect the distribution of many analysed vertebrate species; smaller-bodied amphibians, larger reptiles and medium-sized mammals experience a larger reduction in suitable habitat than other forest-core species.
doi: 10.1038/nature24457
Astrocyte morphogenesis depends on interactions between astrocytic neuroligins and neuronal neurexins.
doi: 10.1038/nature24638
Identifying the gene polymorphisms that are the foundations of variation in glia–neuron signalling in Caenorhabditis elegans provides insight into highly variable age-related declines in worm behaviours.
doi: 10.1038/nature24463
Cryo-electron microscopy structures of the yeast pre-initiation complex (PIC) and its complex with core Mediator provide insights into the opening of promoter DNA and the initiation of transcription.
doi: 10.1038/nature24282
Observations of an event (several energetic eruptions leading to a terminal explosion that is surprisingly hydrogen-rich) with the spectrum of a supernova do not match with other observations of supernovae.
doi: 10.1038/nature24030
In copper components containing highly oriented nanotwins, correlated ‘necklace’ dislocations moving back and forth offer an unusually fatigue-resistant response to engineering stress.
doi: 10.1038/nature24266
Stacking-disordered ice crystallites are shown to have an ice nucleation rate much higher than predicted by classical nucleation theory, which needs to be taken into account in cloud modelling.
doi: 10.1038/nature24279
Analyses of digital corpora of annotated texts reveal the influence of stochastic drift versus selection in grammatical shifts in English and provide a general method for quantitatively testing theories of language change.
doi: 10.1038/nature24455
Experimental evidence that global Kctd13 reduction leads to increased RhoA levels that reduce synaptic transmission, implicating RhoA as a potential therapeutic target for neuropsychiatric disorders associated with copy-number variants that include KCTD13.
doi: 10.1038/nature24470
New silicon probes known as Neuropixels are shown to record from hundreds of neurons simultaneously in awake and freely moving rodents.
doi: 10.1038/nature24636
The discovery of a visual-looming-sensitive neuron, LPLC2, that provides input to the Drosophila escape pathway, and uses dendrites patterned to integrate directionally selective inputs to selectively encode outward motion.
doi: 10.1038/nature24626
Nutrient amendment experiments at the boundary of the South Atlantic gyre reveal extensive regions in which nitrogen and iron are co-limiting, with other micronutrients also approaching co-deficiency; such limitations potentially increase phytoplankton community diversity.
doi: 10.1038/nature24063
Cancer persister cells, which survive cytotoxic treatments, are shown to be sensitive to inhibition of the lipid hydroperoxidase GPX4.
doi: 10.1038/nature24297
Transcriptome-wide mapping of N1-methyladenosine (m1A) at single-nucleotide resolution reveals m1A to be scarce in cytoplasmic mRNA, to inhibit translation, and to be highly dynamic at a single site in a mitochondrial mRNA.
doi: 10.1038/nature24456
