米国では税制改革によって博士課程の学生が不利益を被ることになると考えられ、科学研究や経済に悪影響が及ぶだろう。
Graduate students face alarming tax hike p.271
Adding to PhD students? woes will undermine US research and economy.
doi: 10.1038/d41586-017-05925-6
Adding to PhD students? woes will undermine US research and economy.
doi: 10.1038/d41586-017-05925-6
A Nature journals guide to drawing the structures of molecules should aid expert and casual chemists alike.
doi: 10.1038/d41586-017-05898-6
More international collaboration could build capacity at big physics facilities especially in the south.
doi: 10.1038/d41586-017-05924-7
Bizarre tale of theft and suspicious packages casts doubt on claims for early-human occupation in northern Europe.
doi: 10.1038/nature.2017.22984
Effort aims to help scientists understand how generations of inbreeding have altered the genetics of research rodents.
doi: 10.1038/nature.2017.22974
A former pharmaceutical boss will help navigate the UK's exit from the European Union.
doi: 10.1038/nature.2017.22956
While dealing with their own losses, public-health researchers are regrouping to study the aftermath of Hurricane Maria.
doi: 10.1038/nature.2017.22973
Increased coal use in China appears to be driving the first increase in global greenhouse-gas output since 2014.
doi: 10.1038/nature.2017.22995
Beam generator puts country in elite company for doing experiments in materials science and other fields.
doi: 10.1038/nature.2017.22976
メキシコサンショウウオ(アホロートル)は世界中でペットとして、また実験室でもたくさん飼育されているが、野生では絶滅の危機に瀕している。
doi: 10.1038/d41586-017-05921-w
冥王星の気温は、太陽系の他の惑星体とは異なり、もやによって調節されていることが、今回モデリングから示唆された。この知見は、系外惑星の大気の理解に影響を及ぼす。
doi: 10.1038/551302a
フレクスナー赤痢菌(Shigella flexneri)の感染は、乳児死亡の主な原因である。今回、フレクスナー赤痢菌は、重要な宿主酵素群の一部の分解を誘発するタンパク質を放出することによって、細胞内防御を回避していることが明らかになった。
doi: 10.1038/nature24157
海の微生物の活動は、生物が利用可能な窒素の損失につながる。エルニーニョ/南方振動と呼ばれる気候現象が、この窒素損失の大きさに驚くほど大きな影響を及ぼすことが、今回分かった。
doi: 10.1038/551305a
今回、不治の遺伝性皮膚疾患の患者の治療例によって、遺伝子操作した幹細胞を用いて皮膚をほぼ全て置き換える方法の有効性、実行可能性、安全性が実証された。
doi: 10.1038/nature24753
地球のマントル底部の巨大低せん断速度領域と呼ばれる2つの領域の物理的性質は、よく分かっていない。今回のこうした領域の密度測定は、マントルダイナミクスの理解に影響を及ぼす。
doi: 10.1038/551308a
絶滅のおそれのある生物種に関するデータの統計分析から、変化する人口、農業の状態、経済情勢の下で、保全への投資率がどのように生物多様性に影響を及ぼすかを予測できるモデルが得られた。
doi: 10.1038/nature24158
単一の抗体が、複数の抗ウイルス機序を用いて、マウスやフェレットでのインフルエンザBウイルスの複製を阻害することが分かった。この結果は、改良型インフルエンザワクチンの研究を活気づける可能性がある。
doi: 10.1038/551310a
A Review of the genetics, biochemistry, ecology and evolution of bacterial quorum sensing.
doi: 10.1038/nature24624
An estimate of Earth’s deep-mantle buoyancy is derived from GPS-based measurements of body tide deformation and shown to be dominated by dense material possibly related to subducted oceanic plates or primordial rock.
doi: 10.1038/nature24452
Autologous transgenic epidermal stem cell cultures are used to reconstitute almost the entire epidermis of a patient with severe junctional epidermolysis bullosa.
doi: 10.1038/nature24487
Profiling of 53,193 individual epithelial cells from the mouse small intestine identifies previously unknown cell subtypes and corresponding gene markers, providing insight into gut homeostasis and response to pathogens.
doi: 10.1038/nature24489
IgA+ B cells expressing programmed death ligand 1 (PD-L1) and interleukin 10 accumulate in the inflamed livers of humans and mice with non-alcoholic fatty liver disease where they promote the progression to hepatocellular carcinoma by limiting the local activation of PD-1-expressing CD8+ T cells.
doi: 10.1038/nature24302
Single-molecule fluorescence resonance energy transfer is used to identify the rate-limiting step and new intermediates in the conformational cycle of the Listeria monocytogenes calcium transporter LMCA1.
doi: 10.1038/nature24296
Modelling results find that the temperature of Pluto’s atmosphere is regulated by haze particles rather than gas molecules, suggesting that Pluto should be brighter than previously thought at mid-infrared wavelengths.
doi: 10.1038/nature24465
Sufficiently strong modulation of the interaction strength in a Bose–Einstein condensate induces inelastic atom–atom scattering and causes collective emission of matter-wave jets from the condensate.
doi: 10.1038/nature24272
The relaxation dynamics of granular materials is more like that of complex fluids than that of thermal glass-forming systems, owing to the absence of the ‘cage effect’.
doi: 10.1038/nature24062
Empirical two-part models describe the relationship between conservation spending, human development pressures and biodiversity loss and can inform sustainable development strategies by predicting the effects of financing decisions on future biodiversity losses.
doi: 10.1038/nature24295
In European Neolithic populations, the arrival of farmers prompted admixture with local hunter-gatherers over many centuries, resulting in distinct signatures in each region due to a complex series of interactions.
doi: 10.1038/nature24476
In the mouse caudal brainstem, functionally distinct neuronal subpopulations, which are distinguishable by neurotransmitter identity, connectivity and location, regulate locomotion parameters.
doi: 10.1038/nature24064
A Shigella flexneri type III secretion system effector targets cellular proteins for degradation via the ubiquitin/proteasome pathway, suggesting that such effectors help to overcome defences against bacterial infection.
doi: 10.1038/nature24467
The mechanistic basis for the role of the metabolic enzyme BCAA transaminase 1 (BCAT1) in acute myeloid leukaemias.
doi: 10.1038/nature24294
A signalling mechanism in human cells for sensing DNA damage induced by alkylation involves ubiquitin-dependent recruitment of the alkylation repair complex ASCC to the vicinity of the damage and co-localization with transcription and splicing factors.
doi: 10.1038/nature24484
Application of cryo-electron tomography and subtomogram averaging to determine the structure of the Ebola virus nucleocapsid within intact viruses and recombinant nucleocapsid-like assemblies.
doi: 10.1038/nature24490