今年で生誕250年を数える数学者フーリエの大胆な理論は、今もなお、データ処理をはじめ、あらゆるものに関係している。
Fourier’s transformational thinking p.413
The mathematics of Joseph Fourier, born 250 years ago this week, shows the value of intellectual boldness.
doi: 10.1038/d41586-018-03389-w
The mathematics of Joseph Fourier, born 250 years ago this week, shows the value of intellectual boldness.
doi: 10.1038/d41586-018-03389-w
Dialogue with the public requires a nuanced approach and a willingness to accept uncomfortable truths.
doi: 10.1038/d41586-018-03388-x
Transdisciplinary programme explores the pervasive presence of symmetry violations.
doi: 10.1038/d41586-018-03254-w
Reforms put in place after Ebola epidemic in West Africa have built Nigeria's capacity to diagnose diseases and track their spread.
doi: 10.1038/d41586-018-03171-y
Blacklists that warn against questionable publishers are in demand.
doi: 10.1038/d41586-018-02921-2
Physicist and icon of science dies aged 76.
doi: 10.1038/d41586-018-02957-4
Excavations in Kenya suggest improvements in stone tools and other human changes are linked to variations in climate.
doi: 10.1038/d41586-018-03244-y
Overhaul prompts fears of an erosion in funding for basic science.
doi: 10.1038/d41586-018-03246-w
この20年で数々の期待と論争をもたらしたヒト胚性幹細胞は、生物学の概念を変え、今では臨床現場に登場しようとしている。
doi: 10.1038/d41586-018-03268-4
フルオロキノロン系抗生物質は、まれではあるが極めて重篤で永続的な機能障害を起こすことがあり、その原因を突き止めようと研究が行われている。
doi: 10.1038/d41586-018-03267-5
脳腫瘍は、腫瘍細胞の視覚的評価によって分類されることが多いが、こうした診断は観察者によって異なることがある。今回、分子パターンに注目する機械学習法によって、がん診断を改善できた。
doi: 10.1038/d41586-018-02881-7
レーザーのマイクロ波版であるメーザーの応用は、動作条件が厳しく連続放射ができないため、進んでいなかった。今回、ダイヤモンドメーザーによって、こうした制約が克服された。
doi: 10.1038/d41586-018-03215-3
複雑度の低いタンパク質凝集体は、神経変性の特徴である。あるこうした凝集体の構造の分解能の高いスナップショットによって、こうしたタンパク質が重要な細胞機能を阻害する仕組みに関するこれまでにない描像が得られた。
doi: 10.1038/d41586-018-03000-2
今回、内部太陽系における惑星体のカルシウム同位体組成が、そうした天体の質量と相関していることが分かった。この知見は、太陽系の形成過程の理解に影響を及ぼす可能性がある。
doi: 10.1038/d41586-018-03144-1
今回、2つのグループによって、数千の単一細胞から得られたRNAの塩基配列が解読され、発生中の哺乳類の脳の新皮質における神経系の多様性の起源がこれまでで最も深く調べられた。
doi: 10.1038/d41586-018-02539-4
植物の根の内部の導水組織は、水を通さない細胞に囲まれている。この防護壁は、「通過細胞」によって穴があいており、栄養素の取り込みを調節していると考えられている。今回、こうした細胞が生み出される仕組みが明らかになった。
doi: 10.1038/d41586-018-02861-x
The embryonic emergence of interneuron subtypes in mice is revealed by integrated single-cell transcriptomic analysis along a developmental time course.
doi: 10.1038/nature25999
Analysis of embryonic lethal and sub-viable mouse knockout lines reveals that ablation of many genes affects placental development, and that the occurrence of placental defects is co-associated with abnormal brain, heart and vascular system development.
doi: 10.1038/nature26002
An online approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups has been developed to help to improve current diagnostic standards.
doi: 10.1038/nature26000
The structure of the yeast nuclear pore complex, determined with sub-nanometre precision using an integrative approach that combines a wide range of data, reveals details of its architecture, transport mechanism and evolutionary origins.
doi: 10.1038/nature26003
The massive relic galaxy NGC 1277 has few blue globular clusters, indicating that it has undergone little mass accretion and is a candidate ‘red nugget’ in the nearby Universe.
doi: 10.1038/nature25756
Image reconstruction is reformulated using a data-driven, supervised machine learning framework that allows a mapping between sensor and image domains to emerge from even noisy and undersampled data, improving accuracy and reducing image artefacts.
doi: 10.1038/nature25988
A continuous-wave room-temperature maser is demonstrated by combining a cavity with a high Purcell factor with the narrow linewidth of nitrogen–vacancy defect centres in diamond.
doi: 10.1038/nature25970
Modifying the surfaces and grain boundaries of perovskites with passivating potassium halide layers can mitigate non-radiative losses and photoinduced ion migration, increasing luminescence yields and improving charge transport and interfaces with device electrodes.
doi: 10.1038/nature25989
A lithium–oxygen battery, comprising a lithium carbonate-based protected anode, a molybdenum disulfide cathode and an ionic liquid/dimethyl sulfoxide electrolyte, operates in a simulated air atmosphere with a long cycle life of up to 700 cycles.
doi: 10.1038/nature25984
The mass-independent calcium isotope composition of inner-Solar-System bodies is correlated with their masses and accretion ages, indicating a rapid growth for the precursors of Earth and the Moon during the protoplanetary disk’s lifetime.
doi: 10.1038/nature25990
Youngest Toba Tuff glass shards found together with evidence of human occupation at two archaeological sites from the southern coast of South Africa indicate that early modern humans thrived in this region despite the eruption of the Toba supervolcano about 74,000 years ago.
doi: 10.1038/nature25967
In situ carbon dioxide enrichment experiments show that ocean acidification poses a threat to coral reefs by reducing the saturation state of aragonite and the concentration of carbonate ions and that this impairs community calcification.
doi: 10.1038/nature25968
A multi-tissue gene expression resource representative of the genotypic and phenotypic diversity of modern inbred maize reveals the effect of rare alleles and evolutionary history on the regulation of gene expression.
doi: 10.1038/nature25966
Analysis of gene expression at single-cell resolution in the developing prefrontal cortex of the human embryo reveals a diversity of cell types, elucidates cell lineages and identifies signalling pathways that regulate development.
doi: 10.1038/nature25980
In an Arabidopsis model, repression of cytokinin in the root meristem produces a distinct population of xylem-pole endodermal cells, which resist suberization to become passage cells that enable transport across the otherwise-impermeable endodermis.
doi: 10.1038/nature25976
Phytotransferrin, a functional analogue of transferrin, has an obligate requirement for carbonate to bind iron, which suggests that acidification-driven declines in the concentration of seawater carbonate ions may negatively affect diatom iron acquisition.
doi: 10.1038/nature25982
An improved assay for chromatin accessibility at single-cell resolution in Drosophila melanogaster embryos enables identification of developmental-stage- and cell-lineage-specific patterns of chromatin-level transcriptional regulation.
doi: 10.1038/nature25981
