A high-profile arrest in California shows how the long arm of the law can now extend into DNA databases to check for relatives.
doi: 10.1038/d41586-018-05029-9
To improve health care, researchers need to study diseases as they occur: in combination.
doi: 10.1038/d41586-018-05028-w
Specialist reviewers will be asked to assess if regulations have been followed.
doi: 10.1038/d41586-018-05030-2
NASA’s Mars InSight spacecraft will listen for seismic activity to understand the planet’s core.
doi: 10.1038/d41586-018-04964-x
Clinical trial in Africa helps kids, but raises fears about drug resistance.
doi: 10.1038/d41586-018-04962-z
Teams rush to capture radiation from Universe’s first stars and to explain puzzling observations.
doi: 10.1038/d41586-018-04966-9
With funding still scarce, GP-write project shifts focus to making virus-resistant human cells.
doi: 10.1038/d41586-018-05043-x
Legislation includes proposals to open up the Amazon rainforest to agriculture.
doi: 10.1038/d41586-018-05022-2
European Gaia spacecraft’s first major data dump — the most detailed 3D chart yet of our Galaxy — will keep researchers busy for decades.
doi: 10.1038/d41586-018-04979-4
50年以上続いた内戦が終結を迎えたコロンビアでは、平和な未来の実現に向けて、科学者たちが元戦闘員たちの心理を理解すべく研究を始めている。
doi: 10.1038/d41586-018-04976-7
不適切な細胞の炎症は、疾患の原因になることがある。今回、SAMHD1タンパク質が、新たに複製されたDNAが核から放出されるのを妨げ、望ましくない炎症誘発性応答を抑えることが分かった。
doi: 10.1038/d41586-018-02804-6
系外惑星WASP-107bが親星の軌道を回るにつれて、大気が流出し彗星に似た尾が形成される。今回、こうして流出したガスにヘリウム原子が検出され、系外惑星の大気を調べる強力な手段が得られた。
doi: 10.1038/d41586-018-04969-6
イクチオルニス（Ichthyornis dispar）は、鳥類が祖先である恐竜の特徴を捨て、現在の特徴を進化させた時期の重要な絶滅鳥類である。今回、イクチオルニスの頭蓋の復元から、この変遷の様子が明らかになった。
doi: 10.1038/d41586-018-04780-3
今回、吸水性のゲルがタンパク質結晶の隙間に組み込まれ、注目すべき自己修復材料が生み出された。膨張と収縮を数回繰り返した後でも分子秩序が回復するのである。
doi: 10.1038/d41586-018-04956-x
今回、小さい環が大きい環の穴をすり抜けられるようにすることで、軸上にある2つの環の位置を入れ替えることができる化学系が作られた。この進歩によって、分子データ記憶に応用できる可能性が開かれた。
doi: 10.1038/d41586-018-02732-5
肝移植を待つ人々は、移植臓器が見つかる前に死亡することがあり、移植臓器が得られても質が悪ければ、移植に失敗するリスクがある。肝臓を保存する装置によって、この状況が改善される可能性が出てきた。
doi: 10.1038/d41586-018-04458-w
Analyses of genetic variation and population structure based on over 3,000 cultivated rice (Oryza sativa) genomes reveal subpopulations that correlate with geographic location and patterns of introgression consistent with multiple rice domestication events.
doi: 10.1038/s41586-018-0063-9
Normothermic machine perfusion of the liver improved early graft function, demonstrated by reduced peak serum aspartate transaminase levels and early allograft dysfunction rates, and improved organ utilization and preservation times, although no differences were seen in graft or patient survival.
doi: 10.1038/s41586-018-0047-9
SAMHD1 has an essential role in the replication stress response and prevents inflammation by activating the MRE11 nuclease to degrade nascent DNA strands at stalled replication forks, thus enabling replication.
doi: 10.1038/s41586-018-0050-1
High-resolution cryo-electron microscopy structures of the membrane-pore-forming domain of the mouse gasdermin GSDMA3 show that it forms pores with 26-, 27- or 28-fold symmetry and indicate that it may also form a parallel, soluble, pre-pore ring structure.
doi: 10.1038/s41586-018-0058-6
A detection of helium absorption at 10,833 Å on the exoplanet WASP-107b reveals that its atmosphere is extended and eroding, and demonstrates a new way to study upper exoplanetary atmospheres.
doi: 10.1038/s41586-018-0067-5
The shape of the spectral line and the resonance frequency of the 1S–2S transition in antihydrogen agree very well with those of hydrogen.
doi: 10.1038/s41586-018-0017-2
A strong lightwave in a monolayer of tungsten diselenide drives changes in the valley pseudospin, making valley pseudospin an information carrier that is switchable faster than a single light cycle.
doi: 10.1038/s41586-018-0013-6
An optical-frequency synthesizer based on stabilized frequency combs has been developed utilizing chip-scale devices as key components, in a move towards using integrated photonics technology for ultrafast science and metrology.
doi: 10.1038/s41586-018-0065-7
The integration of macromolecular ferritin protein crystals with hydrogel polymers gives a composite material that expands isotropically and reversibly to twice its size while maintaining periodicity, resists fragmentation and self-heals efficiently.
doi: 10.1038/s41586-018-0057-7
An aluminium compound is synthesized in which the aluminium is formally anionic; reactions with various substrates suggest that this compound acts as the nucleophilic partner in both metal–carbon and metal–metal bond-forming reactions.
doi: 10.1038/s41586-018-0037-y
High-resolution computed tomography of three-dimensionally preserved specimens of Ichthyornis dispar clarifies the mosaic evolution of the avian head, revealing a kinetic feeding apparatus reminiscent of modern birds, a transitional beak and a dinosaurian temporal region.
doi: 10.1038/s41586-018-0053-y
Genome data for thirteen alphaproteobacteria-related clades expand the coverage of alphaproteobacterial diversity and suggest that mitochondria diverged from Alphaproteobacteria before the diversification of all currently known alphaproteobacterial lineages.
doi: 10.1038/s41586-018-0059-5
Trophoblast and embryonic stem cells interact in vitro to form structures that resemble early blastocysts, and the embryo provides signals that drive early trophectoderm development and implantation.
doi: 10.1038/s41586-018-0051-0
The HOIL-1 component of the LUBAC ubiquitin ligase complex is required for LUBAC activity, which prevents lethality during embryogenesis by preventing aberrant TNFR1-mediated endothelial cell death and RIPK1-mediated defects in haematopoiesis.
doi: 10.1038/s41586-018-0064-8
A cryo-EM structure of an initiation complex of HIV-1 reverse transcriptase sheds light on the initiation of reverse transcription of viral RNA.
doi: 10.1038/s41586-018-0055-9
The structure of alternative complex III, a key enzyme in the bacterial electron transport chain, is reported both alone and as a supercomplex with an aa3-type cytochrome c oxidase.
doi: 10.1038/s41586-018-0061-y
