Host countries need to deal with the raised levels of mental-health disorders in migrants if they expect them to integrate well, and that could mean benefits for psychological care in rich countries too.
doi: 10.1038/538139a
‘Nexus’ is enjoying new-found popularity. But what does it actually mean?
doi: 10.1038/538140b
The ExAC database has shown that many mutations thought to be harmful are benign.
doi: 10.1038/538140a
Plans to restrict freedom of movement intensify researchers’ fears over June vote.
doi: 10.1038/nature.2016.20755
Network would be Africa's largest demographics project if it can sustain long-term funding.
doi: 10.1038/nature.2016.20754
Agency looks to time-allocation model in an era of shifting commercial and international interests.
doi: 10.1038/nature.2016.20758
As the first T-cell therapies for tumours near US approval, researchers race to engineer less-toxic alternatives.
doi: 10.1038/538150a
Undergraduates from small, elite institutions have the best chance of winning a Nobel prize.
doi: 10.1038/nature.2016.20757
Jean-Pierre Sauvage, Fraser Stoddart and Bernard Feringa share 2016 award.
doi: 10.1038/nature.2016.20734
世界最大規模のエキソーム解析データによって、ヒトの疾患リスクに関するこれまでの見方が変わってきている。
doi: 10.1038/538154a
ヨーロッパに押し寄せる難民・移民たちは精神疾患を抱える割合が非常に高く、科学者たちはこの状況を改善しようと奮闘している。
doi: 10.1038/538158a
北米のチャネルド・スキャブランドの地形について見直しが行われ、この景観を作り出した古代の洪水は一般に仮定されているより小規模だったことが明らかになった。今回の結果によって、火星で起こったとされる同じような洪水の見積もりも修正される可能性が出てきた。
doi: 10.1038/538174a
人口統計学的解析から、ヒトの寿命には限界があることが今回確証された。これは以前に得られた結果と一致しており、平均余命の延びが近い将来に減速あるいは停止する可能性を示している。
doi: 10.1038/nature19475
月周回衛星によって撮影された画像の分析から、観測期間中に新たに222個のクレーターが生成したことが明らかになった。現在の月面のクレーター生成率は、これまでの予想よりもはるかに高いらしい。
doi: 10.1038/538177a
C4回路と命名された、植物の光合成に関わる経路が見つかってから50年がたち、この効率の良い回路をイネなどの農作物に導入して食料安全保障を維持する試みが続けられている。
doi: 10.1038/538177b
世界のさまざまな地域に存在する多様なヒト集団についての遺伝学的研究から、現生人類が地球全体へ広がっていった分散について、また地形がゲノムの多様性をどのように形作るのかについての手掛かりが得られた。
doi: 10.1038/nature19472
ヒトという種が生じた初期における致死的暴力の発生率は、哺乳類での平均値のほぼ6倍であったと推定されることが今回明らかになったが、これは我々の祖先が大型類人猿であることを考えれば、ほぼ予測される程度の値といえる。
doi: 10.1038/nature19474
Intracellular delivery methods, which are critical to both fundamental research applications and cell-based therapies, are reviewed, concentrating on membrane-disruption-based methods and the use of nanotechnology, microfluidics and laboratory-on-chip technology.
doi: 10.1038/nature19764
A comprehensive review of how analysis of genome sequences provided insights into the origins, evolution and spread of Ebola virus during the 2013–2016 epidemic in West Africa.
doi: 10.1038/nature19790
Deep whole-genome sequencing of 300 individuals from 142 diverse populations provides insights into key population genetic parameters, shows that all modern human ancestry outside of Africa including in Australasians is consistent with descending from a single founding population, and suggests a higher rate of accumulation of mutations in non-Africans compared to Africans since divergence.
doi: 10.1038/nature18964
Whole-genome sequence data for 108 individuals representing 28 language groups across Australia and five language groups for Papua New Guinea suggests that Aboriginal Australians and Papuans diverged from Eurasian populations approximately 60–100 thousand years ago, following a single out-of-Africa dispersal and subsequent admixture with archaic populations.
doi: 10.1038/nature18299
High-resolution ‘before and after’ imaging of the Moon is used to quantify the rate of crater production and provide insights into the cratering process.
doi: 10.1038/nature19829
Semiconducting single crystals of doped barium titanate and titanium dioxide exhibit a flexoelectric-like response upon bending that is much larger than in their undoped, insulating counterparts, reaching unprecedentedly large effective flexoelectric coefficients.
doi: 10.1038/nature19761
Nanometre-scale graphitic capillaries with atomically flat walls are engineered and studied, revealing unexpectedly fast transport of liquid water through channels that accommodate only a few layers of water.
doi: 10.1038/nature19363
Reconstruction of global average surface temperature for the past two million years shows continuous cooling until about 1.2 million years ago, followed by a general flattening, with close coupling of global temperature and atmospheric greenhouse gas concentrations over the past 800,000 years.
doi: 10.1038/nature19798
Simulations of water flow and erosion in Moses Coulee suggest that the floods that carved this canyon only partially filled it, implying much lower flood discharges than previously thought.
doi: 10.1038/nature19817
The percentage of human deaths caused by interpersonal violence reflects our membership of a particularly violent clade of mammals, although changes in socio-political organization have led to marked variations in this proportion.
doi: 10.1038/nature19758
Whole-genome sequencing of individuals from 125 populations provides insight into patterns of genetic diversity, natural selection and human demographic history during the peopling of Eurasia and finds evidence for genetic vestiges of an early expansion of modern humans out of Africa in Papuans.
doi: 10.1038/nature19792
De novo assembly and phasing of the genome of an individual from Korea using a combination of different sequencing approaches provides a useful population-specific reference genome and represents the most contiguous human genome assembly so far.
doi: 10.1038/nature20098
Multi-ancestry genome-wide association analyses for birth weight in 153,781 individuals identified 60 genomic loci in which birth weight and fetal genotype were associated and found an inverse genetic correlation between birth weight and cardiometabolic risk.
doi: 10.1038/nature19806
A mouse study reveals that acetylcholine signalling networks have a role in the regulation of body weight homeostasis, with increased activity of cholinergic neurons decreasing food consumption through downstream hypothalamic targets.
doi: 10.1038/nature19789
Demographic analysis of life expectancy and maximum reported age at death provides evidence that human lifespan has reached its natural limit.
doi: 10.1038/nature19793
Stem cells of the liver, colon and small intestine gradually accumulate mutations throughout life at a similar rate even though cancer incidence varies greatly among these tissues.
doi: 10.1038/nature19768
Genomic duplications in the SOX9 region are associated with human disease phenotypes; a study using human cells and mouse models reveals that the duplications can cause the formation of new higher-order chromatin structures called topologically associated domains (TADs) thereby resulting in changes in gene expression.
doi: 10.1038/nature19800
The CRISPR-associated bacterial enzyme C2c2 is shown to contain two separable, distinct sites for the highly sensitive detection and cleavage of single-stranded RNA.
doi: 10.1038/nature19802
