ノーベル賞は、ブランドの揺るがないあるべき姿を体現している。
Premature burial, show business and the Nobel prize p.5
Awards week shows the value of a strong brand identity.
doi: 10.1038/538005b
Awards week shows the value of a strong brand identity.
doi: 10.1038/538005b
The proposed law would demolish agreements that protect British universities from political interference.
doi: 10.1038/538005a
Lengthening our lives will come at a cost.
doi: 10.1038/538006a
Craft sends back wealth of images in 19-kilometre descent.
doi: 10.1038/nature.2016.20705
Design flaw may have doomed machine at Princeton Plasma Physics Lab.
doi: 10.1038/nature.2016.20710
Ancient genes will soon be available to researchers again, but the move poses its own challenges.
doi: 10.1038/538016a
Panel will focus on the implications of gene editing in human reproduction and livestock.
doi: 10.1038/nature.2016.20713
Japanese biologist Yoshinori Ohsumi recognized for work on autophagy.
doi: 10.1038/nature.2016.20721
British-born theorists recognized for work on topological phases.
doi: 10.1038/nature.2016.20722
機械学習は産業界でも基礎研究でも広く使われるようになっているが、信頼を得るには、まず機械が何をしているのかを理解する必要がある。
doi: 10.1038/538020a
米国メリーランド大学の地理学者Matthew Hansenの研究チームは、衛星データを基に、森林破壊が進んでいる場所をリアルタイムで検出できるマップを作製している。
doi: 10.1038/538024a
固体コバルトをベースとした触媒は、一酸化炭素と水素を合成燃料に変換する反応で商業的に使われている。今回、形態の異なるコバルト触媒を使えば、より価値のある化合物を製造できることが明らかになった。
doi: 10.1038/538044a
転写因子p53の活性低下は腫瘍の発生を引き起こすことがある。SETタンパク質がp53に結合してその活性を阻害するという知見は、腫瘍抑制因子の活性を解き放つ方法の1つを示している。
doi: 10.1038/nature19469
メタンの炭素同位体フィンガープリントのデータベースを使って、全球のメタン収支に対する多様なメタン排出源の寄与が絞り込まれた。今回得られた意外な結果は、気候の予測にも関わってくる。
doi: 10.1038/538046a
ニュートリノは、物質を構成する他の素粒子よりずっと軽い。このことの説明の1つは、ニュートリノは反ニュートリノと同じ粒子であり、新種の「マヨラナ」粒子なのだろうというものだ。今回、1つの実験によって、この仮説に強い制約がかけられた。
doi: 10.1038/nature19473
人類のアフリカから世界各地への分散と定住は、気候の変動に合わせて起こったようだ。この推論は、初期人類の移動の時期に起こった気候変動のコンピューターによるモデル化から引き出されたものである。
doi: 10.1038/nature19471
Weber and Dan review our understanding of the neural circuits controlling sleep, focusing on the advances in measurement and manipulation of neuronal activity and circuit tracing from genetically defined cell types.
doi: 10.1038/nature19773
Structural studies shed light on the function and stoichiometry of the Ton complex, which harnesses the proton motive force across the bacterial inner membrane to transduce energy to the outer membrane.
doi: 10.1038/nature19757
Structures of the human P2X3 receptor in its open, closed, desensitized and antagonist-bound states show the receptor’s gating mechanism and the basis of antagonist binding.
doi: 10.1038/nature19367
The COSIMA mass spectrometer on the Rosetta spacecraft has analysed the solid organic matter found in dust particles emitted by comet 67P/Churyumov–Gerasimenko; this matter is similar to the insoluble organic matter extracted from carbonaceous chondrites such as the Murchison meteorite, but is perhaps more primitive.
doi: 10.1038/nature19320
A hitherto unrecognized type of fermionic excitation in metals is described, which forms a chain of connected loops in momentum space (a nodal chain) along which conduction and valence bands touch.
doi: 10.1038/nature19099
Surface patterning of nanoparticles with polymer patches is achieved in a poor solvent for the polymer by controlling the ratio between the sizes of polymer molecules and nanoparticles.
doi: 10.1038/nature19089
Lower olefins are hydrocarbons that are widely used in the chemical industry, and can be generated from syngas by the ‘Fischer–Tropsch to olefins’ process; here, a new catalyst is described that can generate lower olefins from syngas with high selectivity, with little formation of undesirable methane.
doi: 10.1038/nature19786
Revisions in isotopic source signatures reveal that global total fossil fuel methane emissions from industry plus natural geological seepage are much larger than thought.
doi: 10.1038/nature19797
The dispersal of Homo sapiens across the Arabian Peninsula and the Levant during the last glacial period was not a single event, but occurred in four astronomically-paced migration waves.
doi: 10.1038/nature19365
In the neocortex, sensory information flows into areas specific for a particular modality through parallel thalamocortical circuits, consisting of first order and higher order nuclei connecting to primary and secondary cortical areas, respectively; here, the authors identify common developmental genetic programs that organize these conserved features in parallel sensory pathways.
doi: 10.1038/nature19770
Live fluorescent imaging of murine hippocampal slices shows that NMDAR-dependent glutamate signalling leads to postsynaptic BDNF release, with associated signalling of its receptor, TrkB, on the same dendritic spine, suggesting autocrine BDNF signalling.
doi: 10.1038/nature19766
The three small GTPases Rac1, RhoA and Cdc42 are differentially involved in structural long-term potentiation of rodent dendritic spines, simultaneously ensuring signal specificity and also priming the system for plasticity.
doi: 10.1038/nature19784
Attenuating the lipolysis pathway in Drosophila melanogaster by modulation of the COP1–Arf1 signalling complex induced necrosis in stem cells and led to their engulfment by differentiated cells.
doi: 10.1038/nature19788
A multi-genomic approach identifies the addiction of KRAS-mutant lung cancer cells to XPO1-dependent nuclear export, offering a new therapeutic opportunity.
doi: 10.1038/nature19771
The acidic domain of SET binds and represses unacetylated p53, but this interaction is prevented by cellular-stress-induced p53 CTD acetylation.
doi: 10.1038/nature19759
Gene-editing technology and large-scale proteomics are used to provide insights into the modular assembly of the human mitochondrial respiratory chain complex I, as well as identifying new assembly factors.
doi: 10.1038/nature19754
